AB-102 is a treatment that could offer an alternative to scalp cooling devices for patients undergoing chemotherapy. The status-quo scalp cooling devices restrict the ability of chemotherapy agents to reach hair follicles by decreasing blood flow and cellular metabolism in and around the scalp. This, in turn, prevents chemotherapy drugs from destroying hair follicles. I was surprised to learn that these cooling devices are not well tolerated by some patients simply because the devices are very cold on the scalp and need to be applied for around two hours to be effective.
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